MISSHA Time Revolution Night Repair Ampoule 5X is a 50 ml overnight serum/ampoule listed at $39 at our latest U.S. check. MISSHA says the formula contains 77.2% Extreme Biome with 10 probiotics and is designed as a nourishing night treatment.
Ampoule vs serum
In K-beauty, “ampoule” usually signals a concentrated treatment texture, but there is no universal regulatory definition that makes every ampoule stronger than every serum. Treat it as a format cue, not a guarantee.
What the brand emphasizes
MISSHA centers this line on fermented ingredients and its Extreme Biome complex. The product page describes a nourishing formula intended to support elasticity, radiance and moisture. Those are cosmetic goals; results vary with skin type, routine and consistency.
How to use it
MISSHA recommends applying it after the First Treatment Essence. In a simpler routine, it can go after cleansing and any watery toner/essence, then before moisturizer. Use enough to spread comfortably without forcing extra layers.
Who may prefer it?
- People who enjoy richer overnight routines.
- Those who want a single serum/ampoule step rather than stacking several treatments.
- Shoppers already using Time Revolution who want a coordinated routine.
If your skin is easily overwhelmed by multiple products, introduce it as a replacement for another treatment rather than as an additional layer.
See the current MISSHA US Night Repair offer
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Check MISSHA USOur editorial verdict
Night Repair Ampoule 5X makes the most sense as the main treatment step in an evening routine. Its value depends less on the word “ampoule” and more on whether you enjoy the texture and can use it consistently without overcomplicating your routine.
Editorial note: product specifications and listed prices were checked against current MISSHA US product pages on September 8, 2026. Prices, stock and formulas can change; always verify the current product page before purchasing.